Melanoma Marker (MART-1 + Tyrosinase + gp100)(DT101+ BC199 + T311 + HMB45) , Biotin conjugate , 0.1mg / mL

This antibody cocktail recognizes three melanoma-specific proteins , which include MART-1 , Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed , paraffin-embedded melanomas and other tumors showing melanocytic differentiation.