CD5 (Mantle Cell Lymphoma Marker)(B-B8) , Biotin conjugate , 0.1mg / mL

This antibody recognizes a 67 kDa transmembrane protein which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes , the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells , e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) , mantle cell lymphoma , and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Note that this MAb is not suitable for frozen tissues.