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Spermidine or Spermine N1-Acetyltransferase 1(CPTC-SAT1-3) , Biotin conjugate , 0.1mg / mL

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Spermidine/spermine N1-acetyltransferase 1 (SAT1 or SSAT1) is the key regulatory enzyme in the catabolism of polyamines , catalyzing acetylation of spermidine or spermine to generate N1-acetyl spermidine or N1-acetyl spermine , and N1 , N12-diacetylspermine. The cellular level of SAT1 is normally extremely low , but it is induced rapidly by a variety of stimuli , including polyamines , polyamine analogs , toxic chemicals , certain drugs , and growth factors. Downregulation of SAT1 has been reported in Epstein-Barr virus positive Burkitt's lymphoma cells. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

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