TRIM29(TRIM29/1042) , Biotin conjugate , 0.1mg / mL

This antibody recognizes a 66 kDa protein , which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin , a substrate for the PKC family of protein kinases , and with hPKCI-1 , an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs , suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer , and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy , when used in a panel with TTF-1 , p63 , CK5/6 , and Napsin-A antibodies.Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.