StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker)(STAR/2077) , Biotin conjugate , 0.1mg / mL

Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells , including Leydig cells in the testis , theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone , seminomas and Leydig cell tumors display no specific STAR staining. Therefore , STAR antibody may assist in differentiating sex cord stromal tumors (SCST) , seminomas and embryonal carcinomas. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.