Lactoylglutathione Lyase(CPTC-GLO1-1) , Biotin conjugate , 0.1mg / mL

GLO1 is an enzyme involved in the detoxification of methylgyoxal , a byproduct of glycolysis. GLO1 expression has been demonstrated by several studies to be upregulated in various human malignant tumors , including metastatic melanoma and lung carcinoma , and thus is a target for pharmaceutical development. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.